Resources The Great Plague 1665 - the Black Death Anglo-Spanish Hostility in Early South Carolina, 1670-1748 For Charleston, outbreaks and epidemics are a key part of history 1699 - Yellow Fever Epidemic Charleston, SC Yellow Fever "M" is for Malaria Discus Resources Gale in Context: Elementary - Yellow fever Gale in Context: Elementary - Malaria Gale in Context: Elementary - Smallpox Primary Search - Colonial Diseases Subjects Colonial Beginnings