(fl. 1521) Francisco de Chicora was an Indian slave from South Carolina who was brought back to Spain in 1521.
(ca. 1500-1542) Hernando de Soto was a Spanish explorer and conquistador who explored in South Carolina.
(1617-1675) Hilton Head Island is named after Captain William Hilton, who in 1663, identified a headland near the entrance to Port Royal Sound, which he named “Hilton’s Head” after himself.
(mid to late 1600s-1711) John Lawson was a British explorer, naturalist, and writer who explored the Carolina backcountry and published the first natural historical survey of the area in the book A New Voyage to Carolina.
(fl.1560) Juan Pardo was a Spanish explorer who built missions and forts in the Southeast in 1566 and 1567.