Oconee County takes its name from a Native American word meaning "water eyes of the hills." It was formed in 1868 from Pickens District, and the county seat is Walhalla.
Lexington County and its county seat, the town of Lexington, were named for the battle of Lexington, Massachusetts, the first battle of the American Revolution.
Horry County was named for Revolutionary War hero Peter Horry (1743-1815). The county was originally a part of the Georgetown District, and at one time, it was called Kingston.
Greenwood County takes its name from its county seat, Greenwood. The city of Greenwood was named around 1824 for the plantation of an early resident, John McGehee.
The origin of Fairfield's name is not known, but local legend attributes it to a remark by Lord Cornwallis about the "fair fields" of the area. The county was formed in 1785 as a part of the Camden District.
The origin of the name Edgefield is not clear, although it is usually described as "fanciful." The county was formed in 1785 as part of the Ninety Six District.